ARID4A Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

AT rich interactive domain 4A (RBP1-like)

Gene Aliases

RBP1, RBBP1, RBP-1, RBBP-1

Gene ID

5926

Swiss Prot

P29374

Accession Number

NP_002883

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ARID4A

Target

ARID4A encodes a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described.

Partner Proteins

SUMO2; SUMO1; HDAC1; BRMS1; HIST2H3C; HIST4H4; UBC; CDK2; CDK1; CCNE1; CCNB1; CCNA2; CCND1; CDK4; SIN3A; SAP30; RB1; SIN3B; RBBP7; RBBP4; ARID4B; HDAC3; EID1; HDAC2; ING2; RBL1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

NSSKCTPVKHLNVSKPQKLARSPARISPHIKDGEKDKHREKHPNSSPRTY

Applications

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 86%; Dog: 100%; Guinea Pig: 79%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 86%; Rabbit: 86%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

143kDa

Protein Length

1257

NCBI Gene Symbol

ARID4A

Host or Source

Rabbit

Protein Name

AT-rich interactive domain-containing protein 4A

Gene Name URL

ARID4A

Nucleotide Accession Number

NM_002892

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