What is the catalog number for PLCG1 Antibody - C-terminal region (ARP33086_P050)?

The catalog number for PLCG1 Antibody - C-terminal region (ARP33086_P050) is ARP33086_P050.

What sizes are available for PLCG1 Antibody - C-terminal region (ARP33086_P050)?

PLCG1 Antibody - C-terminal region (ARP33086_P050) is available in the following size(s): 100 µL.

Is PLCG1 Antibody - C-terminal region (ARP33086_P050) in stock?

PLCG1 Antibody - C-terminal region (ARP33086_P050) is currently made to order / not held in immediate stock. Contact us for lead time.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

PLCG1 Antibody - C-terminal region (ARP33086_P050)

Selected Variant

ARP33086_P050

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Name

Phospholipase C, gamma 1

Gene Aliases

PLC1, NCKAP3, PLC-II, PLC148, PLCgamma1

Gene ID

5335

Swiss Prot

P19174

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human PLCG1

Target

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor) -activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

EGFR; UBC; SARNP; WDR61; RIC8A; AASDHPPT; UBR7; EHD4; DPP7; GTF3C4; LIMD1; RPL38; PYGB; ZAP70; KHDRBS1; RASA1; JAK2; JAK1; LCP2; ERBB3; ERBB2; CBL; LAT; VAV1; PDGFRB; INSR; IRS2; NTMT1; SPRY1; NPM1; NCAM1; ALK; PML; IBTK; EEF1A1; BLNK; BAG3; EPOR; CAMK2A

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQISNPEF

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

141 kDa

Protein Length

1290

NCBI Gene Symbol

PLCG1

Host or Source

Rabbit

Protein Name

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

Gene Name URL