POLE3 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Polymerase (DNA directed), epsilon 3 (p17 subunit)

Gene Aliases

P17, YBL1, CHRAC2, CHRAC17, CHARAC17

Gene ID

54107

Swiss Prot

Q9NRF9

Accession Number

NP_059139

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human POLE3

Target

POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.

Partner Proteins

CHRAC1; DRAP1; DR1; UBC; NANS; ANXA6; gag-pol; POLE4; CPSF2; POLE; APP; YEATS2; POLE2; Cebpb; SUMO2; XRCC5; BAZ1A; SMARCA5; RAD17

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MAERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATS

Applications

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

17kDa

Protein Length

147

NCBI Gene Symbol

POLE3

Host or Source

Rabbit

Protein Name

DNA polymerase epsilon subunit 3

Gene Name URL

POLE3

Nucleotide Accession Number

NM_017443

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