MYST2 Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

K (lysine) acetyltransferase 7

Gene Aliases

HBO1, HBOA, MYST2, ZC2HC7

Gene ID

11143

Swiss Prot

O95251

Accession Number

NP_008998

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MYST2

Target

MYST2 belongs to the MYST family, which is characterized by a highly conserved C2HC zinc finger and a putative histone acetyltransferase domain. MYST2 specifically represses AR-mediated transcription. MYST2 is a new AR-interacting protein capable of modulating AR activity. It could play a significant role in regulating AR-dependent genes in normal and prostate cancer cells. The biochemical and genetic interactions of MYST family protein MYST2 with two components of the replication apparatus, MCM2 and ORC1, suggest that MYST2-associated HAT activity may play a direct role in the process of DNA replication. MYST2 is a positive regulatory factor for prereplicative complex assembly.

Partner Proteins

UBC; RNF2; EZH2; VIM; CDK11B; APP; HAP1; BARD1; LRIF1; ING4; JADE1; CSNK1E; DYNC1I1; CDT1; tat; HIST1H4A; HIST1H3A; HIST2H2AC; GMNN; ORC2; MCM2; CDC6; JUN; KIAA1377; CEP70; CBX8; CAAP1; KCTD13; PPID; WDR33; NINL; ZBTB8B; HOOK2; KATNBL1; POLB; CALCOCO2; AT

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLS

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

71kDa

Protein Length

611

NCBI Gene Symbol

KAT7

Host or Source

Rabbit

Protein Name

Histone acetyltransferase KAT7

Gene Name URL

KAT7

Nucleotide Accession Number

NM_007067

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