PIAS3 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Protein inhibitor of activated STAT, 3

Gene Aliases

ZMIZ5

Gene ID

10401

Swiss Prot

Q9Y6X2

Accession Number

NP_006090

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PIAS3

Target

PIAS3 is a member of the protein inhibitor of activated STAT (PIAS) family. It also activates TGF-beta/SMAD transcriptional responses. This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription) ] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier) -E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBC; HIC1; TRIM63; TRIM55; TAB2; SUMO1; CBS; SUMO2; SUMO3; STAT3; NCOA2; CREM; PRPF40A; SERPINA10; GEMIN4; UBE2I; SKIL; HNRNPK; ZFHX3; SERBP1; SATB1; ERBB4; Bcl11a; ELAVL1; PPP1CA; Grm7; Grm8; Grm6; Grm4; TRIM8; RAC1; C19orf60; CARHSP1; UBA1; PSMC1; TRIM2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

DEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDGLQYSPVQGGDPSENKKK

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 86%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Rabbit: 79%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

68kDa

Protein Length

628

NCBI Gene Symbol

PIAS3

Host or Source

Rabbit

Protein Name

E3 SUMO-protein ligase PIAS3

Gene Name URL

PIAS3

Nucleotide Accession Number

NM_006099

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

ABC-TC080D 1 Vial

Canine Lymphatic Fibroblasts

Ask

View Details

248370 50 µL

LZTFL1 (Leucine zipper Transcription Factor-like 1, FLJ36386)

Ask

View Details

YLA0099CT-01 48 Tests

Cat Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) ELISA Kit

Ask

View Details

YLA0099CT-02 96 Tests

Cat Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) ELISA Kit

Ask

View Details

SC205372 10 µg

CSKMT (NM_001043229) Human 3' UTR Clone

Ask

View Details

MBS553986-01 0.05 mg

Biotinylated Human GPA33/A33 Protein Recombinant

Ask

View Details