OLIG2 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Oligodendrocyte lineage transcription factor 2

Gene Aliases

BHLHB1, OLIGO2, RACK17, PRKCBP2, bHLHe19

Gene ID

10215

Swiss Prot

Q13516

Accession Number

NP_005797

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human OLIG2

Target

OLIG2 is a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. OLIG2 is an essential regulator of ventral neuroectodermal progenitor cell fate. It is associated with T-cell acute lymphoblastic leukemia due to a chromosomal translocation t (14;21) (q11.2; q22) . OLIG2 might play a role in learning deficits associated with Down syndrome.

Partner Proteins

CUL3; SRRM1; SOX8; NKX2-2; EP300; SOX10

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

AAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGF

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

32 kDa

Protein Length

323

NCBI Gene Symbol

OLIG2

Host or Source

Rabbit

Protein Name

Oligodendrocyte transcription factor 2

Gene Name URL

OLIG2

Nucleotide Accession Number

NM_005806

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