CHEK1 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Checkpoint kinase 1

Gene Aliases

CHK1

Gene ID

1111

Swiss Prot

O14757

Accession Number

NP_001265

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CHEK1

Target

CHEK1 is required during normal S phase to avoid aberrantly increased initiation of DNA replication, thereby protecting against DNA breakage. Its expression is dispensable for somatic cell death and critical for sustaining G2 DNA damage checkpoint.

Partner Proteins

RELA; CUL4A; UBC; SETMAR; DDB1; TNRC6B; ATR; HECW2; CLSPN; DTL; BTG3; TOPBP1; MAPKAPK2; HSP90AA1; CDC25C; RAD51; PIGM; CUL1; VCP; CDC25A; ATM; APP; MED15; NEK2; TLK1; RB1; BRCA1; FEM1B; XIAP; COPS5; MEPE; LATS2; TP53; Chek1; MEN1; USP7; DNMT1; FANCE; PCNA

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol