NCOR1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Nuclear receptor corepressor 1

Gene Aliases

N-CoR, TRAC1, N-CoR1, hN-CoR, PPP1R109

Gene ID

9611

Swiss Prot

Q60974

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NCOR1

Target

NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p.

Partner Proteins

RARA; TP53; ESR1; PHB2; ZBTB16; THRB; THRA; CREB1; JUN; PPARG; SQSTM1; HDAC3; UBE2I; SOX2; HDAC7; HDAC5; HDAC4; UBC; SKIL; SKI; AR; SMAD4; CSNK2A1; RUNX1T1; CXADR; TBL1XR1; vif; C1D; CHUK; YWHAZ; SMARCE1; SMARCD1; SMARCA2; RBBP4; BPTF; HMGXB4; TAB2; NCOR2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

NENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKK

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 100%; Rat: 92%; Yeast: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

270kDa

Protein Length

2453

NCBI Gene Symbol

NCOR1

Host or Source

Rabbit

Protein Name

Nuclear receptor corepressor 1

Gene Name URL

NCOR1

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