CHD3 Antibody - C-terminal region

Click here to learn more about Aviva's By-Request Conjugation Service.//here

Product Specifications

CAS Number

9007-83-4

Gene Name

Chromodomain helicase DNA binding protein 3

Gene Aliases

ZFH, Mi-2a, SNIBCPS, Mi2-ALPHA

Gene ID

1107

Swiss Prot

Q12873

Accession Number

NP_005843

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CHD3

Target

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Partner Proteins

TRIM28; SUMO2; UBC; LGR4; RNF2; BMI1; SOX2; HDAC2; HDAC1; SIRT1; SKIL; HDAC3; SMARCC2; RBBP7; RBBP4; CHD4; GATAD2A; MBD3; MTA2; IKZF1; GIT1; ZHX1; IMMT; TCERG1; VIM; TP53; TAL1; PTN; NEFL; KPNB1; PIAS4; LRIF1; PRPF40A; HTT; CHD3; BARD1; TWIST1; KDM1A; KDM

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKR

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

220 kDa

Protein Length

2000

NCBI Gene Symbol

CHD3

Host or Source

Rabbit

Protein Name

Chromodomain-helicase-DNA-binding protein 3

Gene Name URL

CHD3

Nucleotide Accession Number

NM_005852.4

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NB100-40833G 0.1 mL

Rabbit Polyclonal USP38 Antibody [DyLight 488]

Ask

View Details

MBS2137642-01 0.1 mL

HRP Linked Monoclonal Antibody to Calponin 2 (CNN2)

Ask

View Details

MBS2137642-02 0.2 mL

HRP Linked Monoclonal Antibody to Calponin 2 (CNN2)

Ask

View Details

MBS2137642-03 0.5 mL

HRP Linked Monoclonal Antibody to Calponin 2 (CNN2)

Ask

View Details

MBS2137642-04 1 mL

HRP Linked Monoclonal Antibody to Calponin 2 (CNN2)

Ask

View Details

MBS2137642-05 5 mL

HRP Linked Monoclonal Antibody to Calponin 2 (CNN2)

Ask

View Details