SIRT6 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Sirtuin 6

Gene Aliases

SIR2L6

Gene ID

51548

Swiss Prot

Q8N6T7

Accession Number

NP_057623

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SIRT6

Target

SIRT6 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by SIRT6 is included in class IV of the sirtuin family.

Partner Proteins

UBC; MDM2; AKT1; STUB1; SKP2; ABCF2; FAF1; VIM; UBE2D1; CHD3; NR0B2; tat; CCNDBP1; RELA; XRCC5; PRKDC; XRCC6; ELF5

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

STASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVG

Applications

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 92%; Dog: 100%; Guinea Pig: 93%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

39kDa

Protein Length

355

NCBI Gene Symbol

SIRT6

Host or Source

Rabbit

Protein Name

NAD-dependent protein deacetylase sirtuin-6

Gene Name URL

SIRT6

Nucleotide Accession Number

NM_016539

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