SIRT7 antibody - middle region (ARP32405_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Sirtuin 7

Gene Aliases

SIR2L7

Gene ID

51547

Swiss Prot

Q9NRC8

Accession Number

NP_057622

Reactivity

Human, Cow, Dog, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SIRT7

Target

SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT7 is included in class IV of the sirtuin family. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

Partner Proteins

DDB1; VPRBP; APP; NOL6; YTHDC2; DDX31; RBM15; ANAPC1; NSD1; NOC3L; UBE2O; RBM25; CCAR2; CHD8; BEND3; PHRF1; DHX37; NUFIP2; CGN; XPO5; LRRC47; BIRC6; WDR18; THOC2; NUP107; REXO4; DDX24; XAB2; UGGT1; ZC3HAV1; YLPM1; NKRF; CCT5; SNW1; DHX30; DIS3; PUF60; COP

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GEEGSHSRKSLCRSREEAPPGDRGAPLSSAPILGGWFGRGCTKRTKRKKV

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol