TLE1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Transducin-like enhancer of split 1 (E (sp1) homolog, Drosophila)

Gene Aliases

ESG, ESG1, GRG1

Gene ID

7088

Swiss Prot

Q04724

Accession Number

NP_005068

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TLE1

Target

TLE1 is a transcriptional corepressor that binds to a number of transcription factors. TLE1 inhibits NF-kappa-B-regulated gene expression and the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. TLE1 has an unusual function as coactivator for ESRRG.

Partner Proteins

TLE1; TCF3; TCF4; UBC; SS18; SSX2; HDAC1; EZH2; ATF2; APH1A; LEF1; TLX3; PROP1; HES1; TLX1; HHEX; FOXG1; ESRRG; EN1; tcf7l1a; NOD2; AES; HESX1; GSK3B; GRB7; NUDT21; DAZAP2; KIAA0408; TSC22D1; TK1; SMN1; RAP1B; GADD45A; CSNK2B; RCC1; CDKN1A; BID; BCL2L1; A

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RNGPEFSNDIKKRKVDDKDSSHYDSDGDKSDDNLVVDVSNEDPSSPRASP

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

83kDa

Protein Length

770

NCBI Gene Symbol

TLE1

Host or Source

Rabbit

Protein Name

Transducin-like enhancer protein 1

Gene Name URL

TLE1

Nucleotide Accession Number

NM_005077

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

141737 200 µL

Osteocalcin (OC, BGLAP, OT, BGP, Bone Gla Protein, Bone Gamma-Carboxyglutamate Protein)

Ask

View Details

MBS6357993-01 0.2 mL

TRAPPC3, NT (TRAPPC3, BET3, Trafficking protein particle complex subunit 3, BET3 homolog) (Azide free) (HRP)

Ask

View Details

MBS6357993-02 5x 0.2 mL

TRAPPC3, NT (TRAPPC3, BET3, Trafficking protein particle complex subunit 3, BET3 homolog) (Azide free) (HRP)

Ask

View Details

MBS621146-01 0.02 mL

Urodilatin (Atrial Natriuretic Peptide)

Ask

View Details

MBS621146-02 0.1 mL

Urodilatin (Atrial Natriuretic Peptide)

Ask

View Details

MBS621146-03 5x 0.1 mL

Urodilatin (Atrial Natriuretic Peptide)

Ask

View Details