AES Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Amino-terminal enhancer of split

Gene Aliases

AES, GRG, ESP1, GRG5, AES-1, AES-2, Grg-5

Gene ID

166

Swiss Prot

Q14CJ1

Accession Number

NP_945320

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human AES

Target

AES is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes.The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

MFAP1; MBNL1; SMAD3; LMO2; LMO1; KRT31; DDX6; CRX; BYSL; BCL6; AES; AEN; CARD9; PARVG; LSM2; HOMEZ; MAGOHB; RNF31; VPS37C; C1orf109; OSGIN1; MED4; PRPF31; GORASP2; KANK2; LDOC1; MTUS2; DIP2A; NCDN; BAHD1; IKZF3; U2AF2; RBPMS; FRS3; NEK6; CALCOCO2; ABI2; T

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

HKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELNSIIRQ

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol