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SKIIP Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

SNW domain containing 1

Gene Aliases

Bx42, SKIP, FUN20, Prp45, SKIIP, SKIP1, PRPF45, NCOA-62

Gene ID

22938

Swiss Prot

Q13573

Accession Number

NP_036377

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SKIIP

Target

SKIIP (Nuclear Protein SkiP, nuclear receptor coactivator NCoA-62, ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly (A) -binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

Partner Proteins

TRAF1; GOLGA2; KRT40; LZTS2; RINT1; TEX11; CEP55; PPIL1; TFIP11; MTUS2; IKZF1; TP53; TUBGCP3; AURKB; UBC; SUZ12; RNF2; BMI1; HECW2; HDAC11; Dlg4; TTC14; ZNF830; SNIP1; CXorf56; XAB2; CTNNBL1; SART1; NHP2L1; MFAP1; EIF4A3; MAGOH; DHX15; DDX5; PABPC1; SKIV2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RQGQSKDKVIYSKYTDLVPKEVMNADDPDLQRPDEEAIKEITEKTRVALE

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

61kDa

Protein Length

536

NCBI Gene Symbol

SNW1

Host or Source

Rabbit

Protein Name

SNW domain-containing protein 1

Gene Name URL

SNW1

Nucleotide Accession Number

NM_012245

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