AXIN2 Antibody - C-terminal region (ARP32099_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Axin 2

Gene Aliases

AXIL, ODCRCS

Gene ID

8313

Swiss Prot

Q9Y2T1

Accession Number

NP_004646

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human AXIN2

Target

AXIN2 is a inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. It probably facilitate the phosphorylation of beta- catenin and APC by GSK3B (By similarity) .

Partner Proteins

FBXW11; GSK3B; GSK3A; UBC; CDC20; AXIN1; KDM5B; ANKRD6; SMAD3; CSNK1E; APC; CTNNB1; APC2; ESR1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QWMLESERQSKPKPHSAQSTKKAYPLESARSSPGERASRHHLWGGNSGHP

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 79%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

92kDa

Protein Length

843

NCBI Gene Symbol

AXIN2

Host or Source

Rabbit

Protein Name

Axin-2

Gene Name URL

AXIN2

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