PAWR Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

PRKC, apoptosis, WT1, regulator

Gene Aliases

PAR4, Par-4

Gene ID

5074

Swiss Prot

O75796

Accession Number

NP_002574

Reactivity

Human, Mouse, Rat, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PAWR

Target

The tumor suppressor WT1 represses and activates transcription. Anti-Prostate Apoptosis Response Protein Par-4 (PAWR) is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.

Partner Proteins

FBXO45; UBC; EED; FAM129B; SNX6; CAND1; VPS29; JMJD6; STAT1; SNX2; SHMT2; SHMT1; PPM1G; IDE; H3F3A; CARS; ATP6V1C1; APEH; PAN2; DRD2; DAPK3; SQSTM1; PRKCZ; Spsb4; Spsb2; SPSB1; FBXO25; HSPA5; Cep350; Kif23; THAP1; SLC5A7; AATF; TFPT; PAWR; WT1; RRAS2; ATP

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

VNIPAAECLDEYEDDEAGQKERKREDAITQQNTIQNEAVNLLDPGSSYLL

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

37kDa

Protein Length

340

NCBI Gene Symbol

PAWR

Host or Source

Rabbit

Protein Name

PRKC apoptosis WT1 regulator protein

Gene Name URL

PAWR

Nucleotide Accession Number

NM_002583

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