MYCN Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

V-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)

Gene Aliases

NMYC, ODED, MODED, N-myc, bHLHe37

Gene ID

4613

Swiss Prot

P04198

Accession Number

NP_005369

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human MYCN

Target

MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. It is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas

Partner Proteins

TRIM32; UBC; HDAC5; NMI; MAX; CDKN2A; GRK5; ZBTB17; SIRT1; YEATS4; CSNK1E; FBXW7; PIAS2; AURKA; SP1; NTRK1; NGFR; HDAC2; CSNK2A1; YAF2; MXD1; CSNK2A2; SLC1A2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EDAPPQKKIKSEASPRPLKSVIPPKAKSLSPRNSDSEDSERRRNHNILER

Applications

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 92%; Rabbit: 77%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

50kDa

Protein Length

464

NCBI Gene Symbol

MYCN

Host or Source

Rabbit

Protein Name

N-myc proto-oncogene protein

Gene Name URL

MYCN

Nucleotide Accession Number

NM_005378

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