RACGAP1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Rac GTPase activating protein 1

Gene Aliases

CYK4, ID-GAP, HsCYK-4, MgcRacGAP

Gene ID

29127

Swiss Prot

Q9H0H5

Accession Number

NP_037409

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RACGAP1

Target

Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC, and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.

Partner Proteins

MORF4L1; UBC; FZR1; MPG; TXNDC11; MPRIP; TANK; KIF23; AURKB; PPP2R4; ECT2; CDK1; IKBKG; CUL1; SH3KBP1; Racgap1; Shcbp1; Cd2ap; YWHAG; YWHAB; PRC1; SH3RF1; SLC26A8; SLC16A10; PRSS23; CHN2; MAP3K4; RND2; MAP3K10; TUBG1; TUBA4A; VAV1; NRAS; GRB2; SFN

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMKAETERSALD

Applications

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol