ESRRA Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Estrogen related receptor alpha

Gene Aliases

ERR1, ERRa, ESRL1, NR3B1, ERRalpha

Gene ID

2101

Swiss Prot

P11474

Accession Number

NP_004442

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human ERR1

Target

The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for this gene.

Partner Proteins

SUMO2; SUMO3; NSD1; NCOA1; EXOSC6; SMARCD3; ESR1; PIAS4; NXF1; ATXN1; MAP2K5; FUS; ADH5; WDR36; ZNF606; C2CD5; IPO13; TFAP4; Cebpb; ESRRG; PPARGC1A; MACF1; EIF3I; NR0B2; NRIP1; NCOA3; TNNI2; SRC; PROX1; DUT; NR0B1; UBC; PARK2; ZNF658B; SPICE1; KDM3B; DPF1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

IEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGE

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol