SUPT16H Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Suppressor of Ty 16 homolog (S. cerevisiae)

Gene Aliases

CDC68, SPT16, FACTP140, SPT16/CDC68

Gene ID

11198

Swiss Prot

Q9Y5B9

Accession Number

EAW66386

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SUPT16H

Target

Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit, the latter of which is SUPT16H.

Partner Proteins

HIST1H2AB; UBC; SUMO2; ATRX; SUMO1; NEDD8; RNF20; PAF1; EED; RNF2; BMI1; rev; FTH1; QRICH1; SRPK2; ICAM1; CD81; IGSF8; PNKP; VCP; FMNL1; SSRP1; ESR1; CENPA; LEO1; RBM25; PRPF6; NCSTN; RTF1; ACIN1; PSIP1; USP39; PRPF8; SF3A1; SAP18; CTR9; DDX21; PRPF3; PRP

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ASKKKVEFLKQIANTKGNENANGAPAITLLIREKNESNKSSFDKMIEAIK

Applications

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

66kDa

Protein Length

602

NCBI Gene Symbol

SUPT16H

Host or Source

Rabbit

Protein Name

FACT complex subunit SPT16

Gene Name URL

SUPT16H

Nucleotide Accession Number

NM_007192

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