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IKZF1 antibody - middle region (ARP31470_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

IKAROS family zinc finger 1 (Ikaros)

Gene Aliases

IK1, LYF1, LyF-1, CVID13, IKAROS, PPP1R92, PRO0758, ZNFN1A1, Hs.54452

Gene ID

10320

Swiss Prot

Q13422

Accession Number

NP_006051

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human IKZF1

Target

IKZF1 binds and activates the enhancer (delta-A element) of the CD3-delta gene. It functions in the specification and the maturation of the T-lymphocyte. It also interacts with a critical control element in the TDT (terminal deoxynucleotidyltransferase) promoter as well as with the promoters for other genes expressed during early stages of B- and T-cell development.

Partner Proteins

PRKAB2; PIN1; FGF12; DDX6; DCX; CTBP2; CTBP1; CKS1B; BYSL; FAM74A4; C1orf174; CEP57L1; ALKBH3; ZMAT2; ZNF417; FRMD6; SPATC1L; FAM161A; FAM214B; ARMC7; NOC4L; SCNM1; C8orf33; AEN; GMCL1P1; KIF9; SH2D4A; CBX8; LMO3; C19orf66; C1orf109; SYT17; ZNF581; FAM50B

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

DLCKIGSERSLVLDRLASNVAKRKSSMPQKFLGDKGLSDTPYDSSASYEK

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 92%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

57kDa

Protein Length

519

NCBI Gene Symbol

IKZF1

Host or Source

Rabbit

Protein Name

DNA-binding protein Ikaros

Gene Name URL

IKZF1

Nucleotide Accession Number

NM_006060

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