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MSX2 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Msh homeobox 2

Gene Aliases

FPP, MSH, PFM, CRS2, HOX8, PFM1

Gene ID

4488

Swiss Prot

P35548

Accession Number

NP_002440

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the n terminal region of human MSX2

Target

MSX2 probable play a morphogenetic role. MSX2 may play a role in limb-pattern formation. In osteoblasts, MSX2 suppresses transcription driven by the osteocalcin FGF response element (OCFRE) .This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

ATXN1; PIAS2; UBC; XRCC5; XRCC6; ZDHHC2; TLE2; TLE1; PPARG; POU2AF1; NR3C1; POLR3D; SPEN; ZBTB17; RUNX2; DLX5; MAGED1; GTF2F2; GTF2F1; MSX1; DLX2; MSX2; CEBPA; PITX2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVE

Applications

IF, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 91%; Rabbit: 91%; Rat: 91%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

29kDa

Protein Length

267

NCBI Gene Symbol

MSX2

Host or Source

Rabbit

Protein Name

Homeobox protein MSX-2

Gene Name URL

MSX2

Nucleotide Accession Number

NM_002449

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