What is the catalog number for NFYA Antibody - C-terminal region?

The catalog number for NFYA Antibody - C-terminal region is ARP31263_T100-25UL.

What sizes are available for NFYA Antibody - C-terminal region?

NFYA Antibody - C-terminal region is available in the following size(s): 25 µL.

Is NFYA Antibody - C-terminal region in stock?

NFYA Antibody - C-terminal region is currently made to order / not held in immediate stock. Contact us for lead time.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

NFYA Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Nuclear transcription factor Y, alpha

Gene Aliases

HAP2, CBF-A, CBF-B, NF-YA

Gene ID

4800

Swiss Prot

P23511

Accession Number

NP_002496

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human NFYA

Target

NFYA is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.

Partner Proteins

LUC7L2; POGZ; NFYB; GTF2A1; CSNK2A1; UBC; APPBP2; TP63; TP53; NFYC; EP300; CDK2; CCNA2; CDC25A; APP; RPS6KA6; JUN; HDAC1; ATF2; SP1; TAF6; TAF11; TAF12; PAPOLG; PWP1; SREBF2; ZHX2; ZHX1; ZHX3; KPNB1; SRSF1; HMGA1; SRF; USF2; USF1; NFYA; NR5A1; POU2F1; CEB

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

YLHESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS

Applications

IHC, WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol