Nfe2 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Nuclear factor (erythroid-derived 2), 45kDa

Gene Aliases

P4, p45, NF-E, NF-E2, p45NF, p45nf-, p45NFE2, p45nf-e2, NF-E2/P45

Gene ID

18022

Swiss Prot

Q07279

Accession Number

NP_032711

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of MOUSE Nfe2

Target

Nfe2 is a component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation.It binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR) . This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. It requires MAFK or other small MAF proteins for binding to the NF-E2 motif. It may play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

Partner Proteins

Psmd4; Kmt2d; Rbbp5; Wdr5; Ash2l; Men1; Mafk; H3f3a; Crebbp; Mapk8; Trip4; Plrg1; Pdlim4; Zfp292; Gtf2h2; Zscan2; Ubp1; Tsg101; Tial1; Supt4a; Snai1; Kdm5d; Kdm5c; Dpf2; Per1; Kat2b; Mybbp1a; Orc2; Ikbkg; Hoxb4; Hoxa4; Hcls1; Gtf2h1; Foxn2; E4f1; Dlx5; Ci

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ARGEADRTLEVMRQQLAELYHDIFQHLRDESGNSYSPEEYVLQQAADGAI

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 79%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

41kDa

Protein Length

373

NCBI Gene Symbol

NFE2

Host or Source

Rabbit

Protein Name

Transcription factor NF-E2 45 kDa subunit

Gene Name URL

Nfe2

Nucleotide Accession Number

NM_008685

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