NR3C1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Gene Aliases

GR, GCR, GRL, GCCR, GCRST

Gene ID

2908

Swiss Prot

P04150

Accession Number

NP_001018086

Reactivity

Human, Mouse, Rat, Cow, Horse, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NR3C1

Target

NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance.

Partner Proteins

TTC5; HSP90AA1; TXN2; UBC; TXN; FKBP5; DCAF6; RABEP2; BRCC3; LARP7; GAPVD1; CD2AP; SF3A1; HNRNPR; TRIM28; HDAC1; MTA2; CCDC6; CENPB; TMF1; PPARG; STUB1; BAG1; RPS6KA5; NCOA1; POLR1D; NCOA2; SRA1; PRKDC; RAD54L2; MAGEA11; PPP5C; PPID; GNB2; GNB1; FKBP4; GN

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MDSKESLTPGREENPSSVLAQERGDVMDFYKTLRGGATVKVSASSPSLAV

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 79%; Horse: 79%; Human: 100%; Mouse: 79%; Pig: 79%; Rabbit: 86%; Rat: 86%; Sheep: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

86kDa

Protein Length

777

NCBI Gene Symbol

NR3C1

Host or Source

Rabbit

Protein Name

Glucocorticoid receptor

Gene Name URL

NR3C1

Nucleotide Accession Number

NM_001018076

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

E51A08582 100 µL

UBCH5 Rabbit mAb

Ask

View Details

Amh1067000 500 ng

GFP hsa-mir-4290 AAV miRNA Vector

Ask

View Details

G4883 96 Tests

PRSS23 (Protease (Serine 23) Guinea Pig ELISA Kit

Ask

View Details

sc-306651 500 mg

2-Amino-6-ethyl-N- (4-methylbenzyl) -4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide

Ask

View Details