NR3C1 antibody - N-terminal region (ARP31090_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Gene Aliases

GR, GCR, GRL, GCCR, GCRST

Gene ID

2908

Swiss Prot

P04150

Accession Number

NP_001018086

Reactivity

Human, Mouse, Rat, Cow, Horse, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NR3C1

Target

NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance.

Partner Proteins

TTC5; HSP90AA1; TXN2; UBC; TXN; FKBP5; DCAF6; RABEP2; BRCC3; LARP7; GAPVD1; CD2AP; SF3A1; HNRNPR; TRIM28; HDAC1; MTA2; CCDC6; CENPB; TMF1; PPARG; STUB1; BAG1; RPS6KA5; NCOA1; POLR1D; NCOA2; SRA1; PRKDC; RAD54L2; MAGEA11; PPP5C; PPID; GNB2; GNB1; FKBP4; GN

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MDSKESLTPGREENPSSVLAQERGDVMDFYKTLRGGATVKVSASSPSLAV

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol