TFCP2 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Transcription factor CP2

Gene Aliases

LSF, SEF, LBP1C, LSF1D, TFCP2C

Gene ID

7024

Swiss Prot

Q12800

Accession Number

NP_005644

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TFCP2

Target

TFCP2 binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1. It also functions as part of the SSP (stage selector protein) complex. TFCP2 facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. It interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.

Partner Proteins

E2F8; NPEPL1; CDC73; MRPL11; KIAA1598; CBX8; TDRD1; CCDC94; ASAP3; C19orf73; FANCL; ZCCHC10; FAM64A; DNAJC27; TRAPPC12; POLL; TSPAN12; PLCB1; STMN2; MORF4L1; FARS2; EIF5B; PITPNM1; PPIG; GPANK1; BAG6; SUMO1; TCEA2; SDCBP; RBMS1; PSMD5; PPP3R2; PHF1; MRPL4

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

YSMSDVLALPIFKQEESSLPPDNENKILPFQYVLCAATSPAVKLHDETLT

Applications

WB, IP

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol