LMO2 Antibody - N-terminal region (ARP30928_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

LIM domain only 2 (rhombotin-like 1)

Gene Aliases

TTG2, LMO-2, RBTN2, RHOM2, RBTNL1

Gene ID

4005

Swiss Prot

P25791-3

Accession Number

NP_005565

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human LMO2

Target

LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.

Partner Proteins

ADAMTSL4; MBIP; HOOK1; TFPT; NOTCH2NL; KRTAP10-7; CCDC36; NUTM1; SPERT; FAM154A; CLHC1; KRT40; SSX2IP; CMTM5; MRFAP1L1; IFT43; C1orf94; LZTS2; TSC22D4; DBF4B; CCDC33; RINT1; NIF3L1; TRIM54; AGTRAP; ZFP64; BANP; STAT3; STAT1; SOX5; SKP1; ROCK1; REL; PRKG1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLS

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

24kDa

Protein Length

227

NCBI Gene Symbol

LMO2

Host or Source

Rabbit

Protein Name

Rhombotin-2

Gene Name URL

LMO2

Nucleotide Accession Number

NM_005574

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