AURKA Antibody - C-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Aurora kinase A
Gene Aliases
AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, PPP1R47
Gene ID
6790
Swiss Prot
O14965
Accession Number
NP_003591
Reactivity
Human, Cow, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human AURKA
Target
AURKA is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. It is found at the centrosome in interphase cells and at the spindle poles in mitosis. This protein may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
Partner Proteins
CHFR; GADD45A; RPLP2; RPLP0; RPL38; RPL30; RPL27; RPL22; RPL12; RPL11; PSMB7; PSMB5; PSMA6; PSMA5; PSMA1; MAPK6; PPP6C; PCMT1; YBX1; NPM1; NCL; MFAP4; LYZ; ILF3; ILF2; IARS; HSPD1; HSP90AB1; HSP90AA1; HSPA9; HSPA8; HSPA5; HSPA2; HSPA1A; HNRNPU; HNRNPA2B1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
ARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
Applications
IHC, WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 80%; Human: 100%; Sheep: 80%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
46kDa
Protein Length
403
NCBI Gene Symbol
AURKA
Host or Source
Rabbit
Protein Name
Aurora kinase A
Gene Name URL
AURKA
Nucleotide Accession Number
NM_003600
Curated Selection
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