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CXCR4 antibody - N-terminal region (ARP30799_P050)

Selected Variant

ARP30799_P050

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Name

Chemokine (C-X-C motif) receptor 4

Gene Aliases

FB22, HM89, LAP3, LCR1, NPYR, WHIM, CD184, LAP-3, LESTR, NPY3R, NPYRL, WHIMS, HSY3RR, NPYY3R, D2S201E

Gene ID

7852

Swiss Prot

P61073

Accession Number

NP_003458

Reactivity

Human, Mouse, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CXCR4

Target

CXCR4 is a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Partner Proteins

UBC; ITCH; nef; P4HB; CD4; env; MYBL2; ST13; ATP13A2; CXCL12; PTPN11; STAM; CAV1; SUMO4; HLA-C; SDC4; HSPA8; GNA13; STAT5B; SOCS3; SOCS1; CCR5; PTK2; STAT2; STAT1; JAK3; DPP4; PTPN6; VAV1; CXCR4; MYH9; PTPRC; JAK2; JAK1; GNAI1; ELANE; CTSG; ADRBK2; ARRB2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MEGISIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFL

Applications

FC, IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Horse: 89%; Human: 91%; Mouse: 77%; Pig: 91%; Rabbit: 85%; Rat: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

40 kDa

Protein Length

352

NCBI Gene Symbol

CXCR4

Host or Source

Rabbit

Protein Name

C-X-C chemokine receptor type 4

Gene Name URL

CXCR4

Nucleotide Accession Number

NM_003467

Price

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