MAP3K8 antibody - N-terminal region (ARP30650_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Mitogen-activated protein kinase kinase kinase 8

Gene Aliases

COT, EST, ESTF, TPL2, AURA2, MEKK8, Tpl-2, c-COT

Gene ID

1326

Swiss Prot

P41279

Accession Number

NP_005195

Reactivity

Human, Mouse, Cow, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MAP3K8

Target

MAP3K8 is a member of the serine/threonine protein kinase family. This kinase can activate both the MAP kinase and JNK kinase pathways. This kinase was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This kinase was

Partner Proteins

RELA; MAP2K1; RIPK1; NFKB1; ACY3; STIP1; HSP90AA1; TAB2; TRAF6; TRAF2; CD40; TNIP2; Nedd4; MAP3K14; MAP2K4; BMPR2; CHUK; REL; AKT1; NFKB2; KSR2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ASEEPAVYEPSLMTMCQDSNQNDERSKSLLLSGQEVPWLSSVRYGTVEDL

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 75%; Horse: 87%; Human: 100%; Mouse: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

53kDa

Protein Length

467

NCBI Gene Symbol

MAP3K8

Host or Source

Rabbit

Protein Name

Mitogen-activated protein kinase kinase kinase 8

Gene Name URL

MAP3K8

Nucleotide Accession Number

NM_005204

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