DYRK3 antibody - N-terminal region (ARP30648_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Dual-specificity tyrosine- (Y) -phosphorylation regulated kinase 3

Gene Aliases

RED, REDK, DYRK5, hYAK3-2

Gene ID

8444

Swiss Prot

O43781

Accession Number

NP_003573

Reactivity

Human, Mouse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DYRK3

Target

This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified.

Partner Proteins

DYRK3; SORL1; FBXO25; PRNP; NEDD4L

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKS

Applications

IF, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%; Mouse: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

66 kDa

Protein Length

588

NCBI Gene Symbol

DYRK3

Host or Source

Rabbit

Protein Name

Dual specificity tyrosine-phosphorylation-regulated kinase 3

Gene Name URL

DYRK3

Nucleotide Accession Number

NM_003582

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