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TP53INP1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Tumor protein p53 inducible nuclear protein 1

Gene Aliases

SIP, Teap, p53DINP1, TP53DINP1, TP53INP1A, TP53INP1B

Gene ID

94241

Swiss Prot

Q96A56

Accession Number

NP_150601

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human TP53INP1

Target

In response to double-strand DNA breaks, TP53INP1 promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis. TP53INP1s and HIPK2 could be partners in regulating p53 activity. TP531NP1 plays a significant role in the progression of anaplastic carcinoma or contributes to anaplastic transformation from papillary or follicular carcinoma.

Partner Proteins

ELAVL1; HIPK2; TP53; E2F4; E2F3; E2F2; E2F1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SFRPSQWIKEHSERQPLNRNSLRRQNLTRDCHPRQVKHNGWVVHQPCPRQ

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 87%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 87%; Pig: 93%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

27kDa

Protein Length

240

NCBI Gene Symbol

TP53INP1

Host or Source

Rabbit

Protein Name

Tumor protein p53-inducible nuclear protein 1

Gene Name URL

TP53INP1

Nucleotide Accession Number

NM_033285

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