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MAP2K4 Antibody - C-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Aliases

JNKK, MEK4, MKK4, SEK1, SKK1, JNKK1, SERK1, MAPKK4, PRKMK4, SAPKK1, SAPKK-1

Gene ID

6416

Swiss Prot

P45985

Accession Number

NP_003001

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human MAP2K4

Target

This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.

Partner Proteins

UBC; EGFR; GEMIN5; MAP3K5; MAP3K1; GCH1; MAPK10; MAPK9; MAPK8; MAPK1; ARRB2; ARRB1; MAP3K7; RBBP8; JUN; MAP2K7; APP; MAP3K2; MAPK14; AKT1; LRRK2; MAP2K4; MAP2K6; MAP3K4; MAP3K3; PML; BLNK; ITCH; MAPK8IP3; ZAK; SPAG9; TRIB1; MAP3K14; CFLAR; MAPK12; EFNA4

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

NLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMA

Applications

WB

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

44kDa

Protein Length

399

NCBI Gene Symbol

MAP2K4

Host or Source

Rabbit

Gene Name URL

MAP2K4

Nucleotide Accession Number

NM_003010

Frequently Asked Questions

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