MAP2K4 Antibody - C-terminal region
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Product Specifications
CAS Number
9007-83-4
Gene Aliases
JNKK, MEK4, MKK4, SEK1, SKK1, JNKK1, SERK1, MAPKK4, PRKMK4, SAPKK1, SAPKK-1
Gene ID
6416
Swiss Prot
P45985
Accession Number
NP_003001
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human MAP2K4
Target
This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.
Partner Proteins
UBC; EGFR; GEMIN5; MAP3K5; MAP3K1; GCH1; MAPK10; MAPK9; MAPK8; MAPK1; ARRB2; ARRB1; MAP3K7; RBBP8; JUN; MAP2K7; APP; MAP3K2; MAPK14; AKT1; LRRK2; MAP2K4; MAP2K6; MAP3K4; MAP3K3; PML; BLNK; ITCH; MAPK8IP3; ZAK; SPAG9; TRIB1; MAP3K14; CFLAR; MAPK12; EFNA4
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
NLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMA
Applications
WB
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1.0 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
44kDa
Protein Length
399
NCBI Gene Symbol
MAP2K4
Host or Source
Rabbit
Gene Name URL
MAP2K4
Nucleotide Accession Number
NM_003010
Frequently Asked Questions
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