BAK1 Antibody - N-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
BCL2-antagonist/killer 1
Gene Aliases
BAK, CDN1, BCL2L7, BAK-LIKE
Gene ID
578
Swiss Prot
Q16611
Accession Number
NP_001179
Reactivity
Human, Horse
Target
BAK1 belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Partner Proteins
BCL2L2; BCL2A1; BCL2L1; BMH1; NFKBIB; HSD17B4; TOMM7; ABCB10; TOMM40; TP53; BAX; MCL1; UBC; DBN1; ARHGDIA; MFN1; BCL2L10; VDAC1; ERN1; BID; BAK1; VDAC2; BCL2; HSPD1; FRYL; SRRM2; MYCBP2; AKAP13; ACTR2; KRT31; FBL; DFFA
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
ASGQGPGPPRQECGEPALPSASEEQVAQDTEEVFRSYVFYRHQQEQEAEG
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Horse: 80%; Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
23kDa
Protein Length
211
NCBI Gene Symbol
BAK1
Host or Source
Rabbit
Protein Name
Bcl-2 homologous antagonist/killer
Gene Name URL
BAK1
Nucleotide Accession Number
NM_001188
Curated Selection
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