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BAK1 antibody - N-terminal region (ARP30473_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

BCL2-antagonist/killer 1

Gene Aliases

BAK, CDN1, BCL2L7, BAK-LIKE

Gene ID

578

Swiss Prot

Q16611

Accession Number

NP_001179

Reactivity

Human, Horse

Target

BAK1 belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Partner Proteins

BCL2L2; BCL2A1; BCL2L1; BMH1; NFKBIB; HSD17B4; TOMM7; ABCB10; TOMM40; TP53; BAX; MCL1; UBC; DBN1; ARHGDIA; MFN1; BCL2L10; VDAC1; ERN1; BID; BAK1; VDAC2; BCL2; HSPD1; FRYL; SRRM2; MYCBP2; AKAP13; ACTR2; KRT31; FBL; DFFA

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ASGQGPGPPRQECGEPALPSASEEQVAQDTEEVFRSYVFYRHQQEQEAEG

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Horse: 80%; Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

23kDa

Protein Length

211

NCBI Gene Symbol

BAK1

Host or Source

Rabbit

Protein Name

Bcl-2 homologous antagonist/killer

Gene Name URL

BAK1

Nucleotide Accession Number

NM_001188

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