NBN Antibody - middle region
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Product Specifications
CAS Number
9007-83-4
Gene Aliases
ATV, NBS, P95, NBS1, AT-V1, AT-V2
Gene ID
4683
Swiss Prot
O60934
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human NBN
Target
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Partner Proteins
ATRX; RPA3; RPA2; RPA1; EP300; CBX8; UBE2N; UBE2D1; UBC; NCL; H2AFX; RNF8; MDC1; TERF2; MRE11A; TERF2IP; RAD50; TLK1; DCLRE1C; RBBP8; BRCA1; MDM2; CCNE1; SKP2; ATM; ATRIP; XRCC5; PRKDC; LIG3; IPO5; HSPA4; ATR; UBE2A; BARD1; BACH1; RAD18; CD3EAP; UBE2B; WR
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
TGLKTTTPGPSLSQGVSVDEKLMPSAPVNTTTYVADTESEQADTWDLSER
Applications
WB
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1.0 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
85kDa
Protein Length
754
NCBI Gene Symbol
NBN
Host or Source
Rabbit
Gene Name URL
NBN
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