TERF1 Antibody - C-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Telomeric repeat binding factor (NIMA-interacting) 1

Gene Aliases

TRF, PIN2, TRF1, TRBF1, t-TRF1, hTRF1-AS

Gene ID

7013

Swiss Prot

P54274

Accession Number

NP_059523

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human TERF1

Target

This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.

Partner Proteins

EP300; SKP1; UBC; ANXA8L1; FBXO4; U2AF1; U2AF2; KDM1A; TINF2; BTRC; TNKS; TCIRG1; SMAD9; BLM; ATM; TNKS2; PINX1; RLIM; DDX19B; PACSIN2; OGFR; TOMM34; WDR4; ARPP21; TRIM16; HEXIM1; PAICS; DNPH1; HMGN4; TUBB4B; TUBB3; AKR1A1; RTN3; PAK4; STUB1; DDX39A; DPP3

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

NLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKLKLISSDSED

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 91%; Dog: 91%; Horse: 91%; Human: 100%; Mouse: 90%; Pig: 91%; Rabbit: 82%; Rat: 91%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

48kDa

Protein Length

439

NCBI Gene Symbol

TERF1

Host or Source

Rabbit

Protein Name

Telomeric repeat-binding factor 1

Gene Name URL

TERF1

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