What is the catalog number for SKP2 Antibody - C-terminal region (ARP30219_P050)?

The catalog number for SKP2 Antibody - C-terminal region (ARP30219_P050) is ARP30219_P050.

What sizes are available for SKP2 Antibody - C-terminal region (ARP30219_P050)?

SKP2 Antibody - C-terminal region (ARP30219_P050) is available in the following size(s): 100 µL.

Is SKP2 Antibody - C-terminal region (ARP30219_P050) in stock?

SKP2 Antibody - C-terminal region (ARP30219_P050) is currently made to order / not held in immediate stock. Contact us for lead time.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

SKP2 Antibody - C-terminal region (ARP30219_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

S-phase kinase-associated protein 2, E3 ubiquitin protein ligase

Gene Aliases

P45, FBL1, FLB1, FBXL1

Gene ID

6502

Swiss Prot

Q13309-4

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human SKP2

Target

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class; in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19) . In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas.

Partner Proteins

USP18; CUL1; CDKN1A; SAMHD1; SUGT1; UBC; AR; RND3; CKS1B; MYC; SMAD7; CDKN1B; SKP1; CDK3; CDK2; LATS2; FZR1; CEP192; SF3B3; KMT2A; E2F1; KPNA6; SIRT3; SIRT4; RBX1; CDC14B; NEDD8; SIRT6; KPNA1; HSP90AA1; EP300; CEBPA; CDH1; BRCA1; BARD1; BTRC; SNRPB2; CDC3

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

TLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQKPSCL

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 92%; Guinea Pig: 83%; Horse: 92%; Human: 100%; Pig: 100%; Rabbit: 100%; Rat: 75%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

23kDa

Protein Length

210

NCBI Gene Symbol

SKP2

Host or Source

Rabbit

Protein Name

S-phase kinase-associated protein 2

Gene Name URL