Amisulbrom

Amisulbrom is a sulfonamide fungicide used to control oomycete diseases. Amisulbrom inhibits the cytochrome-bc1 complex of the mitochondrial electron transport system[1].

Product Specifications

CAS Number

[348635-87-0]

UNSPSC

12352005

Hazard Statement

H319, H351, H410

Target

Apoptosis; Fungal; Mitochondrial Metabolism; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/amisulbrom.html

Purity

99.92

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=S(N1N=C(S(=O)(N2C(C)=C(Br)C3=C2C=C(F)C=C3)=O)N=C1)(N(C)C)=O

Molecular Formula

C13H13BrFN5O4S2

Molecular Weight

466.31

Precautions

H319, H351, H410

References & Citations

[1]Xueying Ma, et al. Amisulbrom causes cardiovascular toxicity in zebrafish (Danio rerio) . Chemosphere. 2021 Nov;283:131236.|[2]Kim M, et al. Amisulbrom induces mitochondrial dysfunction, leading apoptosis and cell cycle arrest in human trophoblast and endometrial cells. Pestic Biochem Physiol. 2025 Apr;209:106347.|[3]Yu Z, et al. Evaluation of Amisulbrom Products for the Management of Clubroot of Canola (Brassica napus) . Plants (Basel) . 2023 Dec 21;13 (1) :28.