What is the catalog number for UCB-J?

The catalog number for UCB-J is HY-136873.

What sizes are available for UCB-J?

UCB-J is available in the following size(s): 5 mg, 10 mM - 1 mL, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does UCB-J come in?

UCB-J is available in 6 different pack sizes.

UCB-J is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures UCB-J?

UCB-J is manufactured by QuantiMol.

What is the estimated delivery time for UCB-J?

Estimated delivery time for UCB-J is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for UCB-J?

The safety data sheet for UCB-J is available here: http://file.medchemexpress.com/batch_PDF/HY-136873/UCB-J-SDS-MedChemExpress.pdf.

UCB-J

UCB-J is a ligand for the synaptic vesicle protein 2A (SV2A) with a pIC50 of 8.2. UCB-J can be used as a PET tracer for SV2A to assist in the diagnosis of epilepsy research[1][2][3][4].

Product Specifications

CAS Number

2242957-52-2

UNSPSC

12352005

Target

Synaptic Vesicle Proteins

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ucb-j.html

Purity

99.62

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C[C@@](C2=CC(F)=C(C(F)=C2)F)([H])CN1CC3=CC=NC=C3C

Molecular Formula

C17H15F3N2O

Molecular Weight

320.31

References & Citations

[1]Joël Mercier, et al. Discovery of heterocyclic nonacetamide synaptic vesicle protein 2A (SV2A) ligands with single-digit nanomolar potency: opening avenues towards the first SV2A positron emission tomography (PET) ligands. ChemMedChem. 2014 Apr;9 (4) :693-8.|[2]Aline Delva, et al. Loss of Presynaptic Terminal Integrity in the Substantia Nigra in Early Parkinson's Disease. Mov Disord. 2020 Aug 7.|[3]Nabeel B Nabulsi, et al. Synthesis and Preclinical Evaluation of 11C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain. J Nucl Med. 2016 May;57 (5) :777-84.|[4]Zhengxin Cai, et al. Synthesis and Preclinical Evaluation of an 18 F-Labeled Synaptic Vesicle Glycoprotein 2A PET Imaging Probe: [ 18 F]SynVesT-2. ACS Chem Neurosci. 2020 Feb 19;11 (4) :592-603.