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APOL1-IN-1

APOL1-IN-1 is a apolipoprotein L1 (APOL1) inhibitor extracted from patent WO2020131807A1 compound 87. APOL1-IN-1 can be used for the research of focal segmental glomerulosclerosis (FSGS) and non-diabetic kidney disease (NDKD) [1].

Product Specifications

CAS Number

[2446817-72-5]

UNSPSC

12352005

Target

Apolipoprotein

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/apol1-in-1.html

Purity

99.85

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H]1C(NC[C@H]1O)=O)CCC2=C(C3=CC=C(F)C=C3)NC4=C2C=CC=C4

Molecular Formula

C21H20FN3O3

Molecular Weight

381.40

References & Citations

[1]Brodney M, et, al. Inhibitors of apol1 and methods of using same. WO2020131807A1.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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