Grapiprant

Product Specifications

CAS Number

415903-37-6

Target

Prostaglandin Receptor

Related Pathways

GPCR/G Protein|||Immunology/Inflammation

Purity

0.9984

Bioactivity

Grapiprant (AAT-007) is a selective EP4 receptor antagonist. Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor (IC50: 35 nM, Ki: 24 nM) .

Smiles

CCc1nc2c(C)nc(C)cc2n1-c1ccc(CCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1

Molecular Formula

C26H29N5O3S

Molecular Weight

491.61

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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