Grapiprant
Product Specifications
CAS Number
415903-37-6
Target
Prostaglandin Receptor
Related Pathways
GPCR/G Protein|||Immunology/Inflammation
Purity
0.9984
Bioactivity
Grapiprant (AAT-007) is a selective EP4 receptor antagonist. Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor (IC50: 35 nM, Ki: 24 nM) .
Smiles
CCc1nc2c(C)nc(C)cc2n1-c1ccc(CCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1
Molecular Formula
C26H29N5O3S
Molecular Weight
491.61
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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