Firategrast
Product Specifications
CAS Number
402567-16-2
Target
Integrin
Related Pathways
Cytoskeletal Signaling
Purity
0.9967
Bioactivity
Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist that reduces the transport of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity. It is used in relapsing-remitting multiple sclerosis, associated with modest reductions in CD4, CD8, and CD19 lymphocyte counts in cerebrospinal fluid.
Smiles
CCOCc1cc(OC)c(c(OC)c1)-c1ccc(C[C@H](NC(=O)c2c(F)cccc2F)C(O)=O)cc1
Molecular Formula
C27H27F2NO6
Molecular Weight
499.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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