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Avosentan

Product Specifications

CAS Number

290815-26-8

Target

Endothelin Receptor

Related Pathways

GPCR/G Protein

Purity

0.9947

Bioactivity

Avosentan (Ro 67-0565; SPP-301) is a potent endothelin receptor (ETA) antagonist with strong inhibitory effects on endothelin-1-induced contraction and may have protective effects against chronic kidney disease. [2]

Smiles

COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OC)-c1ccncc1

Molecular Formula

C23H21N5O5S

Molecular Weight

479.51

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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