Avosentan
Product Specifications
CAS Number
290815-26-8
Target
Endothelin Receptor
Related Pathways
GPCR/G Protein
Purity
0.9947
Bioactivity
Avosentan (Ro 67-0565; SPP-301) is a potent endothelin receptor (ETA) antagonist with strong inhibitory effects on endothelin-1-induced contraction and may have protective effects against chronic kidney disease. [2]
Smiles
COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OC)-c1ccncc1
Molecular Formula
C23H21N5O5S
Molecular Weight
479.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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