Pralsetinib HCl (2097132-94-8 free base)
Product Specifications
Target
Others
Related Pathways
Others
Bioactivity
Pralsetinib is a selective and next-generation RET inhibitor (IC50: 0.3-0.4 nM for WT RET, RET mutants V804L, V804M, M918T, and CCDC6-RET fusion) . BLU-667 is an effective and selective inhibitor of RET mutations, fusions, and predicted resistant mutants.
Smiles
O=C([C@@]1(OC)CC[C@@H](C2=NC(NC3=NNC(C)=C3)=CC(C)=N2)CC1)N[C@H](C4=CC=C(N5N=CC(F)=C5)N=C4)C.[H]Cl
Molecular Formula
C27H33ClFN9O2
Molecular Weight
570.07
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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