Pralsetinib
Product Specifications
CAS Number
2097132-94-8
Target
C-RET
Related Pathways
Apoptosis, Tyrosine Kinase/Adaptors
Purity
0.998
Bioactivity
Pralsetinib (Blu667) (BLU-667) is a highly potent, selective RET inhibitor (IC50s: 0.4, 0.3, 0.4, 0.4, and 0.4 nM for WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion) .
Smiles
CO[C@]1(CC[C@@H](CC1)c1nc(C)cc(Nc2cc(C)[nH]n2)n1)C(=O)N[C@@H](C)c1ccc(nc1)-n1cc(F)cn1
Molecular Formula
C27H32FN9O2
Molecular Weight
533.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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