Fenebrutinib HCl
Product Specifications
CAS Number
2128304-54-9
Target
Others
Related Pathways
Others
Bioactivity
Fenebrutinib is orally available inhibitor of Bruton's tyrosine kinase (BTK) with antineoplastic activity. Upon administration, GDC-0853 inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. This prevents both B-cell activation and BTK-mediated activation of downstream survival pathways, leading to the inhibition of the growth of malignant B-cells that overexpress BTK.
Smiles
Cl.C[C@H]1CN(CCN1c1ccc(Nc2cc(cn(C)c2=O)-c2ccnc(N3CCn4c5CC(C)(C)Cc5cc4C3=O)c2CO)nc1)C1COC1
Molecular Formula
C37H45ClN8O4
Molecular Weight
701.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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